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Evaluating the U.S. Human Genome Project
Cód:
491_9783639128871
This book, Evaluating the U.S. Human Genome Project,presents a comprehensive policy appraisal of alarge-scale science program. Sponsored in the UnitedStates by the National Institutes of Health andDepartment of Energy, the Human Genome Project (HGP)endeavored to sequence a reference human genome. Agenome is the complete set of DNA comprised ofnucleotide bases: adenine, thymine, cytosine, andguanine, in a cells nucleus. The HGPs scientificgoal was to determine the order of these chemicalbases within the 23 pairs of chromosomes. Projectpromoters justified the public investment, $3.3billion, with assurances that the HGP would lead topublic health benefits. Project leaders also pledgedto address harms of genome research and technology byestablishing Ethical, Legal, and Social Implicationsprograms. Though a scientific success, the HGP hasnot lived up to common interest expectations. TheHGPs technical design facilitated efficientsequencing but isolated the project from its largersocial context and excluded non-scientiststakeholders from decision making. The book offersrecommendations to help human genome research andtechnology serve its public purposes.
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